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Profiling Sarcomas—The Search for a Matching Therapy
Imagine if identifying the right cancer treatment for a specific patient was more akin to a dating app where the best potential matches are suggested based on each person’s profile. While progress has...
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Old Dogs Can Teach Cancer Researchers New Tricks
Pets are treasured members of many families, and news that they have developed cancer can hit hard. Sadly, dogs receive a cancer diagnosis at about five times the rate of their owners; in the United...
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A “Gutsy” Approach to Predict Immunotherapy Responses
A recent study suggests that the bacteria in a patient’s gastrointestinal tract—i.e., the gut microbiome—could help clinicians make more informed decisions about immune checkpoint inhibitors (ICIs), a...
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Lymphomas in the Young and the Old: How Do They Differ?
While cancer is often regarded as a disease of old age, 84,100 adolescents and young adults (AYAs) in the United States are expected to be diagnosed with some form of the disease this year, with...
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New Perspectives on the Risk of Secondary Cancers After CAR T-cell Therapy
When the U.S. Food and Drug Administration (FDA) announced in November 2023 that it was investigating a link between receiving CAR T therapy and developing secondary cancers later on, it spurred...
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What Causes Childhood Cancer, and How Are Researchers Helping?
By and large, cancer is the product of decades of damage our cells accumulate through the natural process of existing. Errors arise during the fallible process of DNA replication. Consistent exposure...
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Finding Ways to Overcome Ovarian Cancer’s Resistance to Immunotherapy
Nearly a half century ago, one of the founders of cancer immunology, Lloyd J. Old, MD, predicted that “there is something unique about a cancer cell that distinguishes it from normal cells, and that...
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Pancreatic Cancer: The Search for an Achilles Heel
Pancreatic cancer seems to have a defense against every attack researchers throw its way. It rarely causes symptoms and arises in a hard-to-access organ, complicating prevention and screening...
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Party with a Purpose Supports Geriatric Oncology Research
The risk of cancer increases as we age, but so does the risk of other issues, including additional health conditions and societal challenges. Given the impact these factors can have on a patient’s...
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Neoadjuvant Immunotherapy for Liver Cancer: Shrinking Tumors, Growing Responses
In May 2022, Anibal Torres woke up with severe stomach pain that kept him from eating much over the next several days. He was eventually referred to the hospital for a CT scan that revealed a massive...
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